My research interests focus on investigating the mechanisms of cardiac arrhythmias and anti-arrhythmia therapies using advanced computational modelling.
At the moment, the main three themes of my research are:
Mechanisms of cardiac arrhythmias and defibrillation in acute myocardial ischaemia. This is funded through an MRC Career Development Award involving collaborations with Dr Peter Kohl in the Department of Physiology, Anatomy and Genetics at Oxford, Prof Natalia Trayanova from Johns Hopkins University (USA) and Prof Igor Efimov in Washington University in St Louis (USA).
Modelling drug action on cardiac electrophysiological behaviour.This research is funded through a EU grant called preDiCT, Computational prediction of drug cardiotoxicity, which involves collaborations with academic and industrial partners (including major pharmaceutical companies).
CHASTE, Developing software for realistic heart simulations. Funded by an EPSRC grant with Prof. David Gavaghan, and Drs Joe Pitt-Francis and Jon Whiteley from the Oxford University Computing Laboratory.
In 1997, I graduated as an Electronics Engineer from the Universidad Politecnica de Valencia, Spain. Between 1998 and 2001, I studied my PhD at the Integrated Laboratory of Bioengineering supervised by Prof. Chema Ferrero and worked as an Assistant Professor in Electronics and Biomedical Instrumentation at the Universidad Politecnica de Valencia. My PhD studies aimed at investigating the causes of extracellular potassium accumulation during acute ischaemia using a single cell mathematical model. After graduating in 2001, I joined Prof. Natalia Trayanova's group at Tulane University in New Orleans (now at Johns Hopkins University), as a Postdoctoral Research Fellow. There, we investigated the mechanisms of cardiac vulnerability to electric shocks in normal and globally ischemic hearts. After spending two years in New Orleans, I joined Oxford University in August 2004, as a Senior Postdoctoral Fellow with Prof. David Gavaghan, funded by the Integrative Biology Project. In August 2007, I was awarded an MRC Career Development Award to fund my research in Oxford.
